I was driving the freeway at 65mph and my 92 honda accord LX started to miss. It seemed like I was out of gas. I had a quarter tank. I filled the tank and "just in case" changed the fuel filter. The car ran better, but when I get into the higher speeds (around 2.5rpm) it begins to act like it's out of gas. I let off the throttle for a second and begin throttling again. It goes for a little bit and then begins to miss. If I stomp on the pedal it reacts with plenty of power then starts to miss again when leveling off. So at this time in order to drive my car I am decelerating and accelerating constantly. This is all going on in "Drive". I have an automatic transmission.

 

Also wanted to mention I recently had the head gasket replaced and when checking the plugs noticed the boot on #4 spark plug wire was missing so getting new wires.

 

Have you had your fuel filter replace yet... ?