Any thoughts on if it might be a bad ECM???
Wires are in correct firing order, and the distribute looks fine, I even tried my ignition coil in another car and it ran fine.
I replaced both vtec solenoid and pressure switch. Also, using my OBDII live data feature I compared the O2 sensor voltage to rule out the possibility of low fuel pressure.
If anyone has any other diagnostic ideas I would love to hear them. Thanks.

 

Can you detect actual misfire or are you simply diagnosing misfire based on obd2 codes?

Misfires are usually readily detectable at idle and under acceleration.

good luck

 

Yes I could detect misfire, Idle is jumpy and car lacks power (I know what a Accord should feel like).

 

Won't help with the P1259 but have you cleaned the egr port in the intake?

 

If car is missing and computer is confirming, it's unlikely to be a computer fault causing the missing.

What are long term fuel trim (LTFT) and STFT showing on your obd2 scanner?

The P1259 could be a computer fault. You will need to check the resistance of the pressure switch at the ECU connector. Disconnect correct connector and measure resistance of switch from the correct connector pin to ground. If you measure closed switch, the wiring is good and ECU is fault. If you measure open circuit, then a fault in a wiring or connector somwhere between switch connector and ECU connector.

good luck