First of all I am not a mechanic.lol! My car started running rough after a trip. I pulled the spark plug wires off one by one and when I got to the last one the car shut off after I pulled it off and I can not get it to start back up. It cranks but it doesn't sound like it is firing.
I have been told to replace the wires and plugs, should I replace or do anything else? Please, any help would be greatly appreciated....

 

If the plugs are due, replace them. Get the NGK recommended in the owner's manual, they are ~$2 each. The same goes for the distributor cap and rotor. I would get the cap and rotor at the dealership. Honda spark plug wires last for a long time, so replace with OEM if they look worn out.

Once you update the maintenance items, see if the car will start.

If not, you can use one of the old plugs to test for spark. See the procedure in the tegger site referenced in the sticky thread at the top of the Gen Tech Help forum.

If you left the engine running, and pulled the plug wire, then you could have damaged the coil.

Also, check for engine computer codes. See How to get CEL codes in the DIY section for the procedure on your car.