Before you say it I have had and alignment, new tires, rotation and balance, passenger cv axel replaced, so pretty much the car starts to vibrate a bit at 50 and shakes More the harder I press the gas pedal Through 50-60 then clears up and drives smooth after that, any ideas on what else can cause this

 

Is there movement in the wheel when the front end is up. Have you had the rotors and brakes checked? Ball joints?

 

If you feel shaking in the 50-65 MPH range, but not under and over, then it's likely a tire balance issue or bad tire.
Some tires are "out of round" and just because they balance it doesn't mean they did a good job.

Only other thing I can think of is engine mounts

 

I'm inclined to believe it is either a bad axle (or axles) or a bad tire (or tires). Yes, yes, yes, I know, the OP said the axles have already been replaced. Yeah, about that; my TL, (basically a tarted up Accord) had a speed sensitive vibration which prompted me to change the axles; I swapped in a new set of AutoZone DuraLast axles, and the vibration was maybe slightly improved, but definitely still there. A year later I replaced the axles again, this time with a new pair of APWI (well regarded in Acura circles), and BINGO, smoothness!

By the way @Maudh Alraggad, what kind of car do you have?

 

I have a 2005 accord ex so i bought it like this with the shake thinking it would be a simple fix, since I have had the car I have had brand new tires put on and balance short after, that didn’t work so I got and alignment. After that didn’t work I replaced the axel on the passenger side. Another alignment later it still doing the exact same thing no matter what I do, no better no worse, lastly I jacked the front end up and brought the speed up to 55 no shake

 

Replace both axles with new APWI units and call it done.

 

+1

Always replace axles in pairs. I have an 07 accord and changed my axles 60k miles ago. I had to change them twice and never got the initial take off vibration to disappear. 2 months ago I finally chose to change the brand and all the vibration went away. Thanks to advance auto my old ones still were under warranty so I got a refund.